Emerging Roles of Activity-Dependent Alternative Splicing in Homeostatic Plasticity
نویسندگان
چکیده
منابع مشابه
Emerging roles of BRCA1 alternative splicing.
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Chronic changes in neuronal activity homeostatically regulate excitatory circuitry. However, little is known about how activity regulates inhibitory circuits or specific inhibitory neuron types. Here, we examined the activity-dependent regulation of two neocortical inhibitory circuits--parvalbumin-positive (Parv+) and somatostatin-positive (Som+)--using paired recordings of synaptically coupled...
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Chronic changes in neuronal activity homeostatically regulate excitatory circuitry. However, little is known about how activity regulates inhibitory circuits or specific inhibitory neuron types. Here, we examined the activity-dependent regulation of two neocortical inhibitory circuits – parvalbumin-positive (Parv+) and somatostatin-positive (Som+) – using paired recordings of synaptically coupl...
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Synaptic activity in the central nervous system undergoes rapid state-dependent changes, requiring constant adaptation of the homeostasis between excitation and inhibition. The underlying mechanisms are, however, largely unclear. Chronic changes in network activity result in enhanced production of the inhibitory transmitter GABA, indicating that presynaptic GABA content is a variable parameter ...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2020
ISSN: 1662-5102
DOI: 10.3389/fncel.2020.00104